Explore Fountain
You have questions. We've got answers. Explore the site to learn about our concierge telemedicine programs.
Programs
Information
Explore Fountain
You have questions. We've got answers. Explore the site to learn about our concierge telemedicine programs.
Programs
Information
Explore Fountain
You have questions. We've got answers. Explore the site to learn about our concierge telemedicine programs.
Programs
Information
Vaginal Restore E2 Cream™
Prescription vaginal estradiol to bring back comfort, relieve dryness, and restore the tissue that menopause changed.
Prescription vaginal estradiol to bring back comfort, relieve dryness, and restore the tissue that menopause changed.
This cream was specifically designed to address vaginal symptoms at their source:
This cream was specifically designed to address vaginal symptoms at their source:
Dryness, itching, burning, or irritation
Pain or discomfort during sex
Frequent urinations
Recurrent UTIs
Changes in vaginal odor
Tightness or loss of elasticity
These are all symptoms of what's called GSM (genitourinary syndrome of menopause). It affects the majority of women during and after menopause — and unlike hot flashes, it doesn't get better on its own.
How Vaginal E2 Works
Vaginal estradiol (E2) delivers bioidentical estrogen directly to the vaginal tissue, where it:
Triggers new cell growth
Boosts collagen and natural lubrication
Restores healthy blood flow
Shifts vaginal pH back to its pre-menopausal range
Rebalances the vaginal microbiome
Unlike lubricants or moisturizers, Vaginal E2 actually rebuilds tissue in the vagina. In many patients this leads to more comfort during intimacy, restored urinary function, reduced odor, decreased chance of infection, and increased tightness and elasticity.
What makes this different from other vaginal creams
What makes this different from other vaginal creams
Easy to use. Takes about a minute.
PCCA Science, Technical Report 99823 (2020). In vitro drug release of estriol 0.1% and testosterone 0.1% from VersaBase® Cream and PCCA Ellage™ Anhydrous Vaginal.
Prescription E2 formula
Over-the-counter lubricants may manage symptoms temporarily. This cream delivers bioidentical estrogen directly to the tissue that needs it. It doesn't just soothe — it actually restores and helps rebuild tissue.
Research-backed protocol
Our doctor-designed program starts most patients at daily application for two weeks for fastest relief. Then patients shift to applying 2-3 times weekly. This is the same induction-to-maintenance approach used in published clinical trials on Vaginal E2, designed to restore tissue quickly and then maintain results long-term.
Made with Ellage® cream designed for vaginal tissue
Fountain uses a water-free base called Ellage that was specifically developed for vaginal use. It's gentle, stays in place so the medication absorbs where it's needed, and won't disrupt the vagina's natural moisture or pH balance.
Ellage is made specifically to adhere to the vagina's mucosal lining, meaning that there is little to no leakage, unlike many other vaginal creams. Below is a study done showing its uniquely superior hormone delivery.
Prescription E2 formula
Over-the-counter lubricants may manage symptoms temporarily. This cream delivers bioidentical estrogen directly to the tissue that needs it. It doesn't just soothe — it actually restores and helps rebuild tissue.
Research-backed protocol
Our doctor-designed program starts most patients at daily application for two weeks for fastest relief. Then patients shift to applying 2-3 times weekly. This is the same induction-to-maintenance approach used in published clinical trials on Vaginal E2, designed to restore tissue quickly and then maintain results long-term.
Made with Ellage® cream designed for vaginal tissue
Fountain uses a water-free base called Ellage that was specifically developed for vaginal use. It's gentle, stays in place so the medication absorbs where it's needed, and won't disrupt the vagina's natural moisture or pH balance.
Ellage is made specifically to adhere to the vagina's mucosal lining, meaning that there is little to no leakage, unlike many other vaginal creams. Below is a study done showing its uniquely superior hormone delivery.
Precision dispenser
This medication comes in an expertly designed Topi-CLICK Perl® dispenser. Each click delivers an exact dose — no messy tubes, no measuring, no waste. It comes with a comfortable applicator designed specifically for vaginal use. It's comfortable to use, easy to clean, and is even dishwasher safe.
Prescribed by a hormone expert
This isn't a one-size-fits-all prescription. Your Fountain provider reviews your symptoms, history, and goals to make sure this is the right fit — and adjusts your protocol if anything needs to change. Our medical team reviews your progress after about 10 weeks and adjusts your dose as necessary to ensure you're getting the benefit you need.
Works locally, not systemically
The cream stays in the vaginal tissue where it's applied, and very little estrogen enters the bloodstream. That means the benefits are targeted, and the risk profile is very low — even for patients already on systemic hormone therapy.
What makes this different from what you've tried.
The Topi-CLICK Perl® dispenser makes applying Vaginal Restore E2 Cream simple and precise — no measuring required.
Pricing / What's Included
Many women start feeling a difference within the first few weeks. Full results may take up to 12 weeks — consistency is what makes it work. Here's a typical timeline patients can expect:
Week 1–2 — Tissues begin to rehydrate. Mild improvements in hydration may begin to be felt.
Week 2–4 — Dryness and irritation start to improve. Many women feel a meaningful difference by week 3 or 4.
Week 8–12 — Full benefit — comfort during sex, less urgency, fewer UTIs, tissue that feels like yours again.
Is it safe? Vaginal estradiol at these doses has a strong safety record. Because so little reaches the bloodstream, the risks associated with higher-dose systemic estrogen don't meaningfully apply here. Both the American Urological Association and The Menopause Society endorse low-dose vaginal estrogen as safe and effective for GSM.
Sample message:
"Hi, I am interested in moving forward with the Vaginal Restore E2 Cream."
Our straightforward pricing includes:
Medication: 90-day supply of estradiol (E2) medication in Ellage® cream
Dispenser: Topi-CLICK Perl® cream dispenser with vaginal applicator
Shipping: 2-day shipping via UPS
Care: Ongoing care from the Fountain medical team with 24/7 concierge
Fountain's Vaginal Restore E2 Cream™ treatment is available for just $149 every 90 days (~$50/month).
Ready to get started?
If your Fountain provider has discussed Vaginal Restore E2 Cream™ with you and you'd like to move forward, simply message the Fountain care team to receive a link to a secure checkout page. (833) 967-3100
Vaginal Restore E2 Cream™ is a compounded medication prepared by a licensed compounding pharmacy partner of Fountain in accordance with applicable state and federal regulations. Compounded medications are not reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety, effectiveness, or quality in the same way as commercially manufactured prescription products. Available by prescription only, following evaluation by a licensed Fountain clinician. Individual results may vary. This page is for informational purposes and is not a substitute for personalized medical advice from your clinician. Fountain services and prescription products are available only in states where Fountain's affiliated medical practices are authorized to operate.
PCCA Science, Technical Report 99823 (2020). In vitro drug release of estriol 0.1% and testosterone 0.1% from VersaBase® Cream and PCCA Ellage™ Anhydrous Vaginal.
PCCA Science, Technical Report 99823 (2020). In vitro drug release of estriol 0.1% and testosterone 0.1% from VersaBase® Cream and PCCA Ellage™ Anhydrous Vaginal.
PCCA Science, Technical Report 99823 (2020). In vitro drug release of estriol 0.1% and testosterone 0.1% from VersaBase® Cream and PCCA Ellage™ Anhydrous Vaginal.
Precision dispenser
This medication comes in an expertly designed Topi-CLICK Perl® dispenser. Each click delivers an exact dose — no messy tubes, no measuring, no waste. It comes with a comfortable applicator designed specifically for vaginal use. It's comfortable to use, easy to clean, and is even dishwasher safe.
Prescribed by a hormone expert
This isn't a one-size-fits-all prescription. Your Fountain provider reviews your symptoms, history, and goals to make sure this is the right fit — and adjusts your protocol if anything needs to change. Our medical team reviews your progress after about 10 weeks and adjusts your dose as necessary to ensure you're getting the benefit you need.
Works locally, not systemically
The cream stays in the vaginal tissue where it's applied, and very little estrogen enters the bloodstream. That means the benefits are targeted, and the risk profile is very low — even for patients already on systemic hormone therapy.
Precision dispenser
This medication comes in an expertly designed Topi-CLICK Perl® dispenser. Each click delivers an exact dose — no messy tubes, no measuring, no waste. It comes with a comfortable applicator designed specifically for vaginal use. It's comfortable to use, easy to clean, and is even dishwasher safe.
Prescribed by a hormone expert
This isn't a one-size-fits-all prescription. Your Fountain provider reviews your symptoms, history, and goals to make sure this is the right fit — and adjusts your protocol if anything needs to change. Our medical team reviews your progress after about 10 weeks and adjusts your dose as necessary to ensure you're getting the benefit you need.
Works locally, not systemically
The cream stays in the vaginal tissue where it's applied, and very little estrogen enters the bloodstream. That means the benefits are targeted, and the risk profile is very low — even for patients already on systemic hormone therapy.
Easy to use. Takes about a minute.
Easy to use. Takes about a minute.
The Topi-CLICK Perl® dispenser makes applying Vaginal Restore E2 Cream simple and precise with no measuring required. Patients are provided with instructions on how to apply the applicator to the vagina comfortably and without mess.
The Topi-CLICK Perl® dispenser makes applying Vaginal Restore E2 Cream simple and precise with no measuring required. Patients are provided with instructions on how to apply the applicator to the vagina comfortably and without mess.
What to expect once you start.
What to expect once you start.
Many women start feeling a difference within the first few weeks. Full results may take up to 12 weeks — consistency is what makes it work. Here's a typical timeline patients can expect:
Week 1–2 — Tissues begin to rehydrate. Mild improvements in hydration may begin to be felt.
Week 2–4 — Dryness and irritation start to improve. Many women feel a meaningful difference by week 3 or 4.
Week 8–12 — Full benefit — comfort during sex, less urgency, fewer UTIs, tissue that feels like yours again.
Is it safe? Vaginal estradiol at these doses has a strong safety record. Because so little reaches the bloodstream, the risks associated with higher-dose systemic estrogen don't meaningfully apply here. Both the American Urological Association and The Menopause Society endorse low-dose vaginal estrogen as safe and effective for GSM.
Many women start feeling a difference within the first few weeks. Full results may take up to 12 weeks — consistency is what makes it work. Here's a typical timeline patients can expect:
Week 1–2 — Tissues begin to rehydrate. Mild improvements in hydration may begin to be felt.
Week 2–4 — Dryness and irritation start to improve. Many women feel a meaningful difference by week 3 or 4.
Week 8–12 — Full benefit — comfort during sex, less urgency, fewer UTIs, tissue that feels like yours again.
Is it safe? Vaginal estradiol at these doses has a strong safety record. Because so little reaches the bloodstream, the risks associated with higher-dose systemic estrogen don't meaningfully apply here. Both the American Urological Association and The Menopause Society endorse low-dose vaginal estrogen as safe and effective for GSM.
Pricing / What's Included
Pricing / What's Included
Our straightforward pricing includes:
Medication: 90-day supply of estradiol (E2) medication in Ellage® cream
Dispenser: Topi-CLICK Perl® cream dispenser with vaginal applicator
Shipping: 2-day shipping via UPS
Care: Ongoing care from the Fountain medical team with 24/7 concierge
Fountain's Vaginal Restore E2 Cream™ treatment is available for just $149 every 90 days (~$50/month).
Our straightforward pricing includes:
Medication: 90-day supply of estradiol (E2) medication in Ellage® cream
Dispenser: Topi-CLICK Perl® cream dispenser with vaginal applicator
Shipping: 2-day shipping via UPS
Care: Ongoing care from the Fountain medical team with 24/7 concierge
Fountain's Vaginal Restore E2 Cream™ treatment is available for just $149 every 90 days (~$50/month).
Ready to get started?
Ready to get started?
If your Fountain provider has discussed Vaginal Restore E2 Cream™ with you and you'd like to move forward, simply message the Fountain care team to receive a link to a secure checkout page. (833) 967-3100
If your Fountain provider has discussed Vaginal Restore E2 Cream™ with you and you'd like to move forward, simply message the Fountain care team to receive a link to a secure checkout page. (833) 967-3100
Sample message:
"Hi, I am interested in moving forward with the Vaginal Restore E2 Cream."
Sample message:
"Hi, I am interested in moving forward with the Vaginal Restore E2 Cream."
Vaginal Restore E2 Cream™ is a compounded medication prepared by a licensed compounding pharmacy partner of Fountain in accordance with applicable state and federal regulations. Compounded medications are not reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety, effectiveness, or quality in the same way as commercially manufactured prescription products. Available by prescription only, following evaluation by a licensed Fountain clinician. Individual results may vary. This page is for informational purposes and is not a substitute for personalized medical advice from your clinician. Fountain services and prescription products are available only in states where Fountain's affiliated medical practices are authorized to operate.
Vaginal Restore E2 Cream™ is a compounded medication prepared by a licensed compounding pharmacy partner of Fountain in accordance with applicable state and federal regulations. Compounded medications are not reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety, effectiveness, or quality in the same way as commercially manufactured prescription products. Available by prescription only, following evaluation by a licensed Fountain clinician. Individual results may vary. This page is for informational purposes and is not a substitute for personalized medical advice from your clinician. Fountain services and prescription products are available only in states where Fountain's affiliated medical practices are authorized to operate.
Fountain Vitality-affiliated medical practices are independently owned and operated by licensed physicians who provide services using the Fountain Vitality telehealth platform. For more information about the relationship between Fountain Vitality and the medical practices click here.
Programs
Copyright © 2025 All Rights Reserved by Fountain Vitality Inc.
2064 Park St, Jacksonville, FL 32204
Fountain Vitality-affiliated medical practices are independently owned and operated by licensed physicians who provide services using the Fountain Vitality telehealth platform. For more information about the relationship between Fountain Vitality and the medical practices click here.
Programs
Copyright © 2025 All Rights Reserved by Fountain Vitality Inc.
2064 Park St, Jacksonville, FL 32204
Fountain Vitality-affiliated medical practices are independently owned and operated by licensed physicians who provide services using the Fountain Vitality telehealth platform. For more information about the relationship between Fountain Vitality and the medical practices click here.
Programs
Copyright © 2025 All Rights Reserved by Fountain Vitality Inc.
2064 Park St, Jacksonville, FL 32204
Fountain Vitality-affiliated medical practices are independently owned and operated by licensed physicians who provide services using the Fountain Vitality telehealth platform. For more information about the relationship between Fountain Vitality and the medical practices click here.
Programs
Copyright © 2025 All Rights Reserved by Fountain Vitality Inc.
2064 Park St, Jacksonville, FL 32204