How to Manage Constipation on Semaglutide

Semaglutide is a GLP-1 agonist weight loss medication that works by delaying gastric emptying. In other words, this causes the movement of food to be slowed through the digestive system.

This can lead to constipation, especially if you have previously experienced constipation. In clinical trials, it was noted that 4.5% of patients taking the once weekly injections of semaglutide reported constipation. However, it is important to remember that many people do not experience constipation at all. 

One of the best ways, to manage constipation, is to increase your water intake. An increased water intake will help to keep your stools soft and help to pass the stools when you are trying to have a bowel movement. 

If you are not regularly drinking water, on a daily basis, start with 1L per day.  Tip:  purchase a 1 Liter reusable water bottle, and fill it with water every morning (tap water, filtered water, bubbly water - any water will do!)  Try to drink the water prior to 2pm each day, in order to avoid multiple late night bathroom trips!  

If you are regularly drinking water, on a daily basis, increase your water intake by 10% weekly, to a goal of 1.5 - 2L water per day.  

Increasing your fiber intake will also help with constipation. This can be done through consuming food high in fiber such as beans, broccoli, apples, dried fruits, and bananas. Trying to consume 25g of fiber daily is ideal for the management of constipation. Fiber can also be increased via fiber supplements like Metamucil or Benefiber, or the generic equivalent. 

Exercise reduces constipation, by stimulating bowel movements and keeping things moving within the gastrointestinal tract.  Consider at least 30 minutes of exercise 3-4 times per week, to help to manage constipation. 

If constipation symptoms persist more than 2 days, talk to one of the Fountain Providers about decreasing your dose of semaglutide.  If your constipation is associated with abdominal pain, or any alarming or concerning symptoms, seek immediate medical attention in your closest Emergency Room.